Novel Livestock Vaccines for Viral Diseases in Africa toward Improved Food Security (CIFSRF Phase 2)

Livestock production is a critical industry in Africa, but suffers large losses to preventable viral infections. This project aims to curb the problem. Researchers will fine-tune prototype vaccines, conduct field tests, and take the first steps to commercializing new vaccines. Africa's livestock industry The research will take place in Kenya and South Africa, where livestock production provides food and animal products for local use and export. South Africa's industry accounts for approximately 49% of agricultural gross domestic product, with an average annual turnover of US$13 billion. Vaccines for healthier livestock Vaccination is a critical tool to help reduce the number of livestock losses to viral infections. This project builds on the Canadian International Food Security Research Fund's (CIFSRF) Phase 1 project. Under that earlier phase, Canadian and South African researchers developed a multivalent, live-attenuated (derived from disease-causing pathogens) lumpy skin disease virus vaccine. Lumpy skin disease affects cattle throughout Africa and is spread through insect bites. The vaccine expresses protective antigens to trigger a protective immune response from -sheep and goat pox -peste des petits ruminants -Rift Valley fever In the first phase, the research team also identified candidate African swine fever virus vaccines. Field trials and commercialization This project will complete the research into these specific vaccines for use in South Africa and Kenya. The project team will -conduct vaccine field trials to evaluate its efficacy -facilitate vaccine licensing and manufacturing by commercial vaccine producers -provide training and gather data from socio-economic studies The goal is to help small-scale livestock farmers who are transitioning to commercial production to use the vaccines. These vaccines are critical. They will enhance food security by increasing production efficiency and reducing the numbers of animals lost to disease. This project is funded under the Canadian International Food Security Research Fund (CIFSRF), a program of IDRC undertaken with the financial support of the Government of Canada provided through Foreign Affairs, Trade and Development Canada (DFATD).

Project ID

107848

Project status

Active

Start Date

Friday, July 11, 2014

Duration

41 months

IDRC Officer

Kevin Tiessen

Total funding

CA$ 4,973,300

Country(s)

Kenya, South Africa

Project Leader

Lorne A. Babiuk

Institution

The Governors of The University of Alberta

Institution Country

Canada

Institution Website

http://www.ualberta.ca

Project Leader

David Wallace

Institution

Agricultural Research Council

Institution Country

South Africa

Institution Website

http://www.arc.agric.za