Scoping study for a one-health response to knowledge gaps in antimicrobial resistance research
The spread of antimicrobial resistance (AMR) has been dramatically accelerated by overuse and misuse of antimicrobials. As a result, antimicrobial drugs are rapidly losing their effectiveness. Many of the great public health achievements of the past century are at risk, including the reduction in mortality from infectious diseases, increased access to health services, and availability of safe, effective, and affordable medicines. A recent World Bank report finds that drug-resistant infections have the potential to cause economic damage similar to, and likely worse than, that inflicted by the 2008 financial crisis. The worst impacts are projected to be on the poorest countries and people.
The objective of the project, implemented in partnership with the International Bank for Reconstruction and Development (a component of the World Bank Group), is to develop an AMR research agenda for low and middle-income countries. This will be achieved by conducting a comprehensive literature review of interdisciplinary and intervention-focused AMR research related to human health, agriculture, water and sanitation, environment, trade, food security, economic growth, and poverty. The study will include an assessment of current knowledge gaps, as well as existing capacities and ongoing efforts, with a particular focus on the Global South.
The project will also identify and prioritize the most promising research areas for further advancement of the AMR containment agenda.